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Insulin resistance is the new standard of metabolic wellness

What is insulin resistance?

Insulin resistance is the decrease in the responsiveness of cells to insulin. If insulin resistance is present, cells in our body cannot utilize glucose, and blood glucose levels become remain high. As a result, the pancreas produces much more insulin in response to increased insulin sensitivity to keep the blood glucose level at a healthy range.

Glucose is present in food, and its levels increase after eating. Insulin is one of the main hormones that regulates glucose uptake into cells as a fuel for energy production. Increasing blood glucose levels trigger insulin production by the pancreas to keep blood sugar levels in a healthy range. High levels of insulin in the body trigger several unhealthy disease pathways.

A sedentary lifestyle, obesity and a diet high in sugar/carbohydrates are some of the main contributors to insulin resistance.

Why is insulin resistance important?

Insulin resistance affects a significant portion of the world's population. Without intervention, insulin resistance can contribute to chronic, complex diseases such as obesity, type 2 diabetes and cardiovascular disease.

What happens when you have insulin resistance?

Increased insulin production, due to insulin resistance, results in a condition called hyperinsulinemia. The increased insulin level in the body causes impairs many steps of energy metabolism. This leads to weight gain and contributes to worsening insulin resistance. Over time, chronic insulin resistance may lead to prediabetes and type 2 diabetes. In parallel, blood pressure, cholesterol, blood sugar and triglyceride levels rise, and a condition called metabolic syndrome may develop. The vascular structures may be damaged and cause cardiovascular diseases due to hyperinsulinemia.

Taken together, the early diagnosis and treatment of insulin resistance critically important.

What are the symptoms?

Struggling with one or more of these symptoms over time may indicate you have decreased insulin sensitivity, which can lead to more serious, chronic diseases.

Weakness

Fatigue

Feeling Hungry Even After A Meal

Thirst or Hunger

Getting Tired Faster than Usual

Silent

How is insulin resistance currently measured?

The gold-standard test for measuring insulin resistance is the hyperinsulinemic euglycemic clamp test, which is performed in hospital settings. The other insulin resistance measurement test is the Homa-IR test, where blood samples are tested for glucose and insulin and insulin resistance is calculated. Blood samples are collected by a self-collection device or a phlebotomist and sent back to the laboratory for analysis.

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Insulin resistance is a decrease in the sensitivity of cells to insulin and can greatly affect quality of life. The condition is becoming increasingly prevalent worldwide and is associated with complex, chronic diseases like obesity, type 2 diabetes and cardiovascular disease.

Learn how to measure your insulin sensitivity and optimize your unique metabolism

Insulin resistance is the new standard of metabolic wellness

What is insulin resistance?

What happens when you have insulin resistance?

We draw our strength from science.

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